Association between intercellular adhesion molecule-1 to depression and blood-brain barrier penetration in cerebellar vascular disease

Table 4 Comparison of the mean Ktrans values of the region of interest regions between the cerebral small vessel disease group and the control group

Regions	CSVD group	Control group	Significance	Mean difference	95%CI
					Lower	Upper
ROI1	2.509 ± 1.082	2.166 ± 0.897	0.046	0.343	0.007	0.680
ROI2	2.698 ± 0.987	2.695 ± 1.287	0.988	0.003	-0.374	0.380
ROI3	1.529 ± 0.748	0.901 ± 0.51	< 0.001	0.628	0.419	0.837
ROI4	1.571 ± 0.888	0.949 ± 0.654	< 0.001	0.622	0.366	0.878

CI: Confidence interval; CSVD: Cerebral small vessel disease; ROI: Region of interest.