Association between 5-HTR1A gene C-1019G polymorphism and antidepressant response in patients with major depressive disorder: A meta-analysis

Table 3 Meta-analysis results of serotonin 1A receptor polymorphism gene C-1019G polymorphism and antidepressant efficacy in the effective treatment group

Genetic model	Odds ratio	95%CI	P value (association)	Model type (heterogeneity)	P value (heterogeneity)	I² (heterogeneity)	Egger's test P value	Begg's test P value
Allelic Model (G vs C)	0.86	0.69–1.12	0.23	Random	0.02	46.46	0.64	0.83
Dominant model (CG vs CC)	0.81	0.71–1.09	0.13	Fixed	0.26	15.81	0.10	0.09
Recessive model (GG vs CC)	0.80	0.60–1.31	0.37	Random	0.04	40.64	0.25	0.21
Dominant model (CG+GG vs CC)	0.80	0.59–1.09	0.23	Random	0.04	33.66	0.10	0.08
Locus model (GG vs CG+CC)	1.15	0.90–1.47	0.20	Fixed	0.907	0.00	0.29	0.16
Unfitted model (CC+GG vs GC)	0.97	0.82–1.20	0.95	Fixed	0.52	0.00	0.64	0.21