Psychological stress impact neurotrophic factor levels in patients with androgenetic alopecia and correlated with disease progression

Table 3 Comparison of neurotrophic factors between non-stress and stress groups, mean ± SD

Neurotrophic factor	Non-stress group (n = 30)	Stress group (n = 90)	t-value	P value
NGF (pg/mL)	24.65 ± 5.32	22.18 ± 4.76	2.264	0.028
BDNF (ng/mL)	9.61 ± 2.14	8.46 ± 1.85	2.637	0.011
NT-3 (pg/mL)	15.89 ± 3.76	17.48 ± 3.21	2.077	0.044
NT-4 (ng/mL)	7.73 ± 1.64	8.89 ± 1.47	3.44	0.001
GDNF (pg/mL)	12.45 ± 2.78	11.18 ± 2.35	2.244	0.030

NGF: Nerve growth factor; BDNF: Brain-derived neurotrophic factor; GDNF: Glial cell-derived neurotrophic factor; NT: Neurotrophin.