Hippocampus protection from apoptosis by Baicalin in a LiCl-pilocarpine-induced rat status epilepticus model through autophagy activation

Figure 4 The number of LC3-II-positive neurons was partially decreased by SE and increased by Baicalin. 3-Methyladenine reversed the Baicalin-induced alteration. A: Representative immunofluorescence staining; B: Positive neuronal cells were analyzed. n = 6. ^aP < 0.05 and ^bP < 0.01 vs the relevant group. The number of LC3-II-positive cells/0.5-mm-long subfield of the hippocampus under a light microscope was regarded as the numerical value (scale bar = 50 μm). SE: Status epilepticus; 3-MA: 3-Methyladenine.