Hippocampus protection from apoptosis by Baicalin in a LiCl-pilocarpine-induced rat status epilepticus model through autophagy activation

Figure 2 Baicalin ameliorated status epilepticus-induced neuronal apoptosis. A: Transferase dUTP nick end labeling staining was performed; B: Neuronal apoptosis was analyzed. Baicalin protects the hippocampus from apoptosis following status epilepticus (SE), and 3-Methyladenine reverses Baicalin-induced neuroprotection in hippocampal neurons. Data are represented as mean ± SD. (n = 5), ^bP < 0.01 vs the SE group; ^cP < 0.05 vs the SE + B group. Scale bar = 50 μm. SE: Status epilepticus; TUNEL: Transferase dUTP nick end labeling; 3-MA: 3-Methyladenine.