Past, present, and future of deep transcranial magnetic stimulation: A review in psychiatric and neurological disorders

Table 2 Development of deep transcranial magnetic stimulation in obsessive-compulsive disorder

Ref.	Method	Result	Adverse events	Significance
Modirrousta et al[30], 2015	1 Hz DTMS stimulates PFC	Improvement in Y-BOCS	Electric shocking sensation	Low frequency deep rTMS was effective in OCD symptom reduction
Carmi et al[27], 2018	20 Hz or 1 Hz DTMS stimulates mPFC and ACC	Improvement in Y-BOCS	Slight headache	DTMS has the ability to directly modify ACC activity
Carmi et al[31], 2019	20 Hz DTMS stimulates mPFC and ACC	Improvement in Y-BOCS	Slight headache	High-frequency DTMS in special region can significantly improve OCD symptoms
Ikawa et al[33], 2022	20 Hz DTMS stimulates mPFC and ACC	Improvement in Y-BOCS	Slight headache	DTMS treatment of OCD had a favorable therapeutic effect
Ikawa et al[33], 2022	20 Hz DTMS stimulates mPFC and ACC	Improvement in Y-BOCS	Electric shocking sensation	DTMS was found to be a safe and effective intervention for OCD symptoms in adolescents

Y-BOCS: Yale-Brown obsessive compulsive scale; mPFC: Medial prefrontal cortex; ACC: Anterior cingulate cortex; DTMS: Deep transcranial magnetic stimulation; PFC: Prefrontal cortex; OCD: Obsessive-compulsive disorder.