Dexmedetomidine mediates the mechanism of action of ferroptosis in mice with Alzheimer’s disease by regulating the mTOR-TFR1 pathway

Figure 2 Comparison of the level of Fe²⁺ in mouse hippocampal neurons in the different treatment groups. A: Green fluorescence represents intracellular iron levels, and quenching of calcein fluorescence reflects iron uptake by chondrocytes. Scale bar: 20 μm; B: Fluorescence intensity. ^aP < 0.05, compared with the blank group; ^bP < 0.05, compared with the amyloid β group; ^cP < 0.05, compared with the dexmedetomidine group. Aβ: Amyloid β; Dex: Dexmedetomidine; si-mTOR: Mammalian target of rapamycin siRNA; DAPI: 4’,6-diamidino-2-phenylindole.