Glutamate decarboxylase 1 gene polymorphisms are associated with respiratory symptoms in panic disorder

Table 4 Hamilton Anxiety Rating Scale subdimension scores of panic disorder with different glutamate decarboxylase 1 rs1978340 and rs3749034 polymorphisms

Variable	rs1978340			F	P value	rs3749034			F	P value
	A/A (n = 17)	A/G (n = 88)	G/G (n = 125)			A/A (n = 17)	A/G (n = 97)	G/G (n = 116)
HAMA1	1.59 ± 1.06	1.88 ± 1.16	1.81 ± 1.18	0.439	0.645	1.82 ± 1.33	1.81 ± 1.14	1.82 ± 1.17	0.001	0.999
HAMA2	2.00 ± 1.00	2.06 ± 0.94	2.17 ± 1.11	0.402	0.669	2.24 ± 1.30	2.07 ± 1.01	2.13 ± 1.03	0.206	0.814
HAMA3	1.94 ± 1.09	1.66 ± 1.07	1.98 ± 1.08	2.295	0.103	2.24 ± 1.25	1.78 ± 1.01	1.85 ± 1.11	1.260	0.286
HAMA4	1.71 ± 1.11	1.43 ± 1.11	1.58 ± 1.02	0.728	0.484	1.47 ± 0.87	1.48 ± 1.02	1.58 ± 1.12	0.231	0.794
HAMA5	1.59 ± 1.06	1.58 ± 1.04	1.65 ± 1.03	0.121	0.886	1.65 ± 1.17	1.55 ± 1.06	1.67 ± 0.99	0.402	0.670
HAMA6	1.53 ± 1.01	1.25 ± 1.05	1.54 ± 0.99	2.255	0.107	1.65 ± 1.32	1.38 ± 1.07	1.44 ± 0.94	0.498	0.747
HAMA7	1.76 ± 1.03	1.34 ± 0.99	1.62 ± 1.01	2.459	0.088	1.59 ± 1.06	1.46 ± 1.01	1.56 ± 1.02	0.277	0.759
HAMA8	1.06 ± 0.83	1.38 ± 1.10	1.37 ± 1.12	0.644	0.526	1.41 ± 0.94	1.34 ± 1.10	1.34 ± 1.11	0.032	0.969
HAMA9	2.06 ± 1.20	1.91 ± 0.99	1.94 ± 1.03	0.154	0.858	1.82 ± 1.13	2.08 ± 1.07	1.84 ± 0.97	1.647	0.195
HAMA10	2.88 ± 0.93	1.94 ± 0.98	1.90 ± 1.02	7.445	0.001	2.41 ± 1.00	1.94 ± 0.96	1.97 ± 1.08	1.601	0.204
HAMA11	0.76 ± 0.66	0.86 ± 0.79	0.97 ± 0.91	0.672	0.512	1.00 ± 0.94	0.89 ± 0.87	0.92 ± 0.82	0.143	0.867
HAMA12	1.00 ± 1.00	1.20 ± 0.96	1.34 ± 0.92	1.214	0.299	1.41 ± 1.00	1.22 ± 0.93	1.28 ± 0.95	0.340	0.712
HAMA13	1.12 ± 0.93	1.35 ± 0.87	1.30 ± 1.03	0.427	0.653	1.29 ± 1.11	1.25 ± 0.99	1.36 ± 0.92	0.377	0.687
HAMA14	1.59 ± 1.06	1.48 ± 0.98	1.35 ± 0.98	0.693	0.501	1.53 ± 1.28	1.44 ± 0.99	1.38 ± 0.94	0.229	0.796
HAMA total	22.59 ± 5.22	21.34 ± 6.94	22.50 ± 6.97	0.799	0.451	23.53 ± 7.13	21.70 ± 6.93	22.16 ± 6.75	0.535	0.587

HAMA1: Anxious mood; HAMA2: Tension; HAMA3: Fears; HAMA4: Insomnia; HAMA5: Intellectual; HAMA6: Depressed mood; HAMA7: Somatic complaints muscular; HAMA8: Somatic complaints sensory; HAMA9: Cardiovascular symptoms; HAMA10: Respiratory symptoms; HAMA11: Gastrointestinal symptoms; HAMA12: Genitourinary symptoms; HAMA13: Autonomic symptoms; HAMA14: Behavior at interview; HAMA: Hamilton Anxiety Rating Scale.