Glutamate decarboxylase 1 gene polymorphisms are associated with respiratory symptoms in panic disorder

Table 3 Panic disorder severity scale subdimension scores of panic disorder with different glutamate decarboxylase 1 rs1978340 and rs3749034 polymorphisms

Variable	rs1978340			F	P value	rs3749034			F	P value
	A/A (n = 17)	A/G (n = 88)	G/G (n = 125)			A/A (n = 17)	A/G (n = 97)	G/G (n = 116)
PDSS1	2.12 ± 0.93	2.11 ± 1.09	2.14 ± 1.08	0.022	0.978	1.94 ± 0.97	2.06 ± 1.04	2.22 ± 1.10	0.837	0.434
PDSS2	2.41 ± 1.00	2.32 ± 1.00	2.44 ± 1.10	0.349	0.706	2.35 ± 1.41	2.28 ± 1.07	2.49 ± 0.97	1.099	0.335
PDSS3	2.41 ± 1.18	2.08 ± 0.89	2.14 ± 1.05	0.786	0.457	2.18 ± 1.13	1.99 ± 1.00	2.26 ± 0.98	1.934	0.147
PDSS4	1.59 ± 1.28	1.57 ± 1.04	1.66 ± 1.06	0.218	0.804	1.41 ± 1.12	1.76 ± 1.12	1.53 ± 1.00	1.590	0.206
PDSS5	1.71 ± 1.26	1.91 ± 1.01	1.76 ± 1.10	0.581	0.560	2.12 ± 1.22	1.67 ± 0.93	1.89 ± 1.63	1.818	0.165
PDSS6	2.33 ± 1.22	2.15 ± 0.97	2.11 ± 1.03	0.417	0.660	2.18 ± 1.33	2.09 ± 1.03	2.18 ± 0.97	0.206	0.814
PDSS7	1.59 ± 0.94	1.83 ± 1.01	1.97 ± 1.18	1.087	0.339	2.00 ± 1.06	1.85 ± 1.05	1.91 ± 1.15	0.174	0.841
PDSS total	14.18 ± 4.68	13.97 ± 3.39	14.23 ± 3.86	0.132	0.877	14.18 ± 4.99	13.70 ± 3.54	14.47 ± 3.69	1.134	0.323

PDSS1: Panic attack frequency, PDSS2: Panic distress, PDSS3: Severity of anticipatory anxiety, PDSS4: Agoraphobic fear/avoidance, PDSS5: Fear/avoidance of panic-related sensations, PDSS6: Work impairment, PDSS7: Social impairment, PDSS: Panic Disorder Severity Scale.