Identification and characterization of noncoding RNAs-associated competing endogenous RNA networks in major depressive disorder

Table 3 The significant Gene Ontology terms identified in this study

Category	Term description	Count of genes	P value
Biology process	Activin receptor signaling pathway	3	5.54E-05
Biology process	Peripheral nervous system development	3	0.000292
Biology process	G protein-coupled receptor internalization	2	0.0003
Biology process	Desensitization of G protein-coupled receptor signaling pathway	2	0.000487
Biology process	Negative adaptation of signaling pathway	2	0.000487
Biology process	Positive regulation of vascular endothelial growth factor receptor signaling pathway	2	0.000487
Biology process	Adaptation of signaling pathway	2	0.000597
Biology process	Uterus development	2	0.000656
Biology process	Sphingolipid biosynthetic process	3	0.000679
Biology process	Reproductive structure development	5	0.00078
Cellular component	Glutamatergic synapse	4	0.002395
Cellular component	Schaffer collateral-CA1 synapse	2	0.00786
Cellular component	Cul2-RING ubiquitin ligase complex	1	0.024149
Cellular component	Integral component of synaptic membrane	2	0.025933
Cellular component	Intrinsic component of synaptic membrane	2	0.029786
Cellular component	Extracellular matrix	3	0.044750
Cellular component	Podosome	1	0.047732
Cellular component	Excitatory synapse	1	0.075303
Cellular component	Integral component of postsynaptic density membrane	1	0.079823
Cellular component	Intrinsic component of postsynaptic density membrane	1	0.084321
Molecular function	Receptor ligand activity	6	0.000191
Molecular function	Hormone activity	3	0.001352
Molecular function	UDP-glycosyltransferase activity	3	0.002314
Molecular function	Guanyl-nucleotide exchange factor activity	4	0.002772
Molecular function	Growth factor activity	3	0.003326
Molecular function	Transferase activity, transferring hexosyl groups	3	0.006074
Molecular function	Phosphatidylinositol-4,5-bisphosphate 3-kinase activity	2	0.006746
Molecular function	Cytokine activity	3	0.007189
Molecular function	Phosphatidylinositol bisphosphate kinase activity	2	0.007334
Molecular function	Transcription factor activity, RNA polymerase II proximal promoter sequence-specific DNA binding	4	0.008356