Haplotype analysis of long-chain non-coding RNA NONHSAT102891 promoter polymorphisms and depression in Chinese individuals: A case-control association study

Table 2 Stratified analyses of the rs6230 and rs3792747 polymorphisms in depressed patients

Variables	Frequency (%)		Adjusted OR (95%CI)	P value
rs6230
Depressive episode	Severe	Mild
TT	100 (39.7)	70 (30.7)	1.00 (Ref)
TC	125 (49.6)	125 (54.8)	1.57 (1.05-2.36)	0.28
CC	27 (10.7)	33 (14.5)	1.69 (0.92-3.09)	0.088
TC/CC	152 (60.3)	158 (69.3)	1.59 (1.08-2.35)	0.019
Suicide attempt	Yes	No
TT	102 (34.9)	68 (36.2)	1.00 (Ref)
TC	154 (52.7)	96 (51.1)	1.06 (0.70-1.63)	0.78
CC	36 (12.3)	24 (12.8)	0.87 (0.45-1.68)	0.68
TC/CC	190 (65.1)	120 (63.8)	1.02 (0.68-1.54)	0.91
First-episode patient	Yes	No
TT	88 (35.5)	82 (35.3)	1.00 (Ref)
TC	131 (52.8)	119 (51.3)	1.07 (0.71-1.60)	0.75
CC	29 (11.7)	31 (13.4)	1.15 (0.63-2.10)	0.66
TC/CC	160 (64.5)	150 (64.7)	1.08 (0.73-1.58)	0.70
Family history	Yes	No
TT	37 (39.4)	133 (34.5)	1.00 (Ref)
TC	47 (50)	203 (52.6)	1.29 (0.79-2.11)	0.31
CC	10 (10.6)	50 (12.9)	1.44 (0.66-3.14)	0.35
TC/CC	57 (60.6)	253 (65.5)	1.30 (0.81-2.07)	0.28
rs3792747
Depressive episode	Severe	Mild
TT	176 (69.8)	150 (65.8)	1.00 (Ref)
TC/CC	76 (30.2)	78 (34.2)	1.21 (0.82-1.80)	0.33
Suicide attempt	Yes	No
TT	201 (68.8)	125 (66.5)	1.00 (Ref)
TC/CC	91 (31.2)	63 (33.5)	1.14 (0.75-1.72)	0.54
First-episode patient	Yes	No
TT	168 (67.7)	158 (68.1)	1.00 (Ref)
TC/CC	80 (32.3)	74 (31.9)	0.98 (0.66-1.44)	0.9
Family history	Yes	No
TT	64 (68.1)	262 (67.9)	1.00 (Ref)
TC/CC	30 (31.9)	124 (32.1)	1.00 (0.62-1.63)	1.00

Odds ratio was adjusted by age and gender. OR: Odds ratio; CI: Confidence interval.