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©The Author(s) 2023.
World J Psychiatry. Dec 19, 2023; 13(12): 1005-1015
Published online Dec 19, 2023. doi: 10.5498/wjp.v13.i12.1005
Published online Dec 19, 2023. doi: 10.5498/wjp.v13.i12.1005
Table 1 Genetic model genotype and allele frequencies of two long-chain non-coding RNA NONHSAT102891 promoter polymorphisms among depressed patients and controls and association with risk of depression, n (%)
| Models | Polymorphisms | Control (n = 329) | Patients (n = 480) | Adjusted OR (95%CI) | P value |
| rs6230 | |||||
| Codominant | TT | 109 (33.1) | 170 (35.4) | 1 | |
| TC | 173 (52.6) | 250 (52.1) | 0.91 (0.66-1.24) | 0.53 | |
| CC | 47 (14.3) | 60 (12.5) | 0.82 (0.52-1.30) | 0.41 | |
| Dominant | TT | 109 (33.1) | 170 (35.4) | 1 | |
| TC/TT | 220 (66.9) | 310 (64.6) | 0.79 (0.57-1.10) | 0.17 | |
| Recessive | TT/TC | 282 (85.7) | 420 (87.5) | 1 | |
| CC | 47 (14.3) | 60 (12.5) | 0.77 (0.49-1.23) | 0.28 | |
| Allele | T | 391 (59.4) | 590 (61.5) | 1 | |
| C | 267 (40.6) | 370 (38.5) | 0.92 (0.75-1.12) | 0.40 | |
| rs3792747 | |||||
| Codominant | TT | 208 (63.2) | 326 (67.9) | 1 | |
| TC | 113 (34.3) | 137 (28.5) | 0.77 (0.57-1.05) | 0.17 | |
| CC | 8 (2.4) | 17 (3.5) | 1.36 (0.57-3.20) | 0.48 | |
| Dominant | TT | 208 (63.2) | 326 (67.9) | 1 | |
| TC/CC | 121 (36.8) | 154 (32.1) | 0.84 (0.60-1.17) | 0.31 | |
| Recessive | TT/TC | 321 (97.6) | 463 (96.5) | 1 | |
| CC | 8 (2.4) | 17 (3.5) | 1.47(0.63-3.45) | 0.36 | |
| Allele | T | 529 (80.4%) | 789 (82.2) | 1 | 0.65 |
| C | 129 (19.6) | 171 (17.8) | 0.89 (0.69-1.15) | 0.36 |
- Citation: Li Y, Wang YX, Tang XM, Liang P, Chen JJ, Jiang F, Yang Q, Liang YD. Haplotype analysis of long-chain non-coding RNA NONHSAT102891 promoter polymorphisms and depression in Chinese individuals: A case-control association study. World J Psychiatry 2023; 13(12): 1005-1015
- URL: https://www.wjgnet.com/2220-3206/full/v13/i12/1005.htm
- DOI: https://dx.doi.org/10.5498/wjp.v13.i12.1005