Serum neuronal pentraxin 2 is related to cognitive dysfunction and electroencephalogram slow wave/fast wave frequency ratio in epilepsy

doi:10.5498/wjp.v13.i10.714

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World Journal of Psychiatry

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World J Psychiatry. Oct 19, 2023; 13(10): 714-723
Published online Oct 19, 2023. doi: 10.5498/wjp.v13.i10.714

Table 1 Baseline data for epilepsy patients with different cognitive function and healthy volunteers

Variable	Control (n = 30)	Epilepsy		P value
Variable	Control (n = 30)	Normal (n = 74)	ECD (n = 37)	P¹	P²
Age (yr, mean ± SD)	33.93 ± 9.39	35.27 ± 9.73	34.68 ± 9.50	0.523	0.760
Gender, n (%)
Male	17	48 (64.86)	20 (54.05)	0.434	0.270
Female	13	26 (35.14)	17 (45.95)	0.434	0.270
Education level, n (%)
Junior/senior high school	19	46 (62.16)	20 (54.05)	0.911	0.412
University or above	11	28 (27.84)	17 (45.95)	0.911	0.412
Epilepsy onset age (yr, mean ± SD)	–	26.15 ± 7.41	25.62 ± 10.52	–	0.760
Epilepsy duration (yr, mean ± SD)	–	9.12 ± 5.60	9.05 ± 4.10		0.948
Epilepsy type, n (%)
Focal	–	20 (27.03)	9 (24.32)	–	0.760
Overall	–	54 (72.97)	28 (75.68)	–	0.760
Types of epilepsy drugs, n (%)
0–1	–	57 (77.03)	26 (70.27)	–	0.440
2–3	–	17 (22.97)	11 (29.73)	–	0.440
Epilepsy treatment protocol, n (%)
VPN	–	39 (52.70)	19 (51.35)	–	0.890
No-VPN	–	35 (47.30)	18 (48.65)	–	0.890

¹Control group vs. epilepsy (normal) group.

²Epilepsy (normal) group vs. epilepsy patients with cognitive dysfunction group.

ECD: Epilepsy patients with cognitive dysfunction; VPN: Valproate.

Citation: Huang XF, Xu MX, Chen YF, Lin YQ, Lin YX, Wang F. Serum neuronal pentraxin 2 is related to cognitive dysfunction and electroencephalogram slow wave/fast wave frequency ratio in epilepsy. World J Psychiatry 2023; 13(10): 714-723
URL: https://www.wjgnet.com/2220-3206/full/v13/i10/714.htm
DOI: https://dx.doi.org/10.5498/wjp.v13.i10.714