Clinical and Translational Research
Copyright ©The Author(s) 2023.
World J Psychiatry. Jan 19, 2023; 13(1): 15-35
Published online Jan 19, 2023. doi: 10.5498/wjp.v13.i1.15
Table 6 Results of repeated measures analysis of covariance for outcome variables
Dependent variable
Covariate
Independent variable
Degrees of freedom
F value
P value
Bonferroni adjusted pairwise comparisons
HADS depressionGenderTimepoint (within subjects)2, 420.1580.855Baseline (mean 11.77 SD 0.78) vs post-treatment (mean 7.75, SD 0.73), P = 0.003Baseline vs follow-up (mean 7.55, SD 0.89), P < 0.001Post treatment vs follow-up, P = 1.0
Employment (between subjects)1, 219.7880.005Employed vs unemployed mean difference1 -3.96 (95%CI: -6.60 to -1.33); employed have lower mean score at all three time points
AgeTimepoint (within subjects)2, 420.5950.556Baseline (mean 11.85 SD 0.77) vs post-treatment (mean 7.78, SD 0.74), P = 0.002Baseline vs follow-up (mean 7.62, SD 0.89), P < 0.001Post treatment vs follow-up, P = 1.0
Employment (between subjects)1, 2111.2660.003Employed vs unemployed mean difference1 -4.33 (95% CI: -7.02 to -1.65); employed have lower mean score at all three time points
HADS AnxietyGenderTimepoint (within subjects)2, 440.0140.986Baseline (mean 14.54 SD 0.77) vs post-treatment (mean 10.33, SD 0.75), P < 0.001Baseline vs follow-up (mean 10.38, SD 0.86), P < 0.001Post treatment vs follow-up, P = 1.0
WHO disability scale totalGenderTimepoint (within subjects)1.24, 22.3820.35420.7042Baseline (mean 85.32 SD 8.72) vs post-treatment (mean 65.83, SD 7.42), P = 0.143Baseline vs follow-up (mean 53.59, SD 8.26), P = 0.014Post treatment vs follow-up, P = 0.016
Living alone (between subjects)1, 188.2880.010Living alone vs with someone mean difference1 37.82 (95%CI: 10.22 to 65.42); living alone have higher score at all three timepoints
Employment (between subjects)1, 1810.6740.004Employed vs unemployed mean difference1 -30.52 (95%CI: -50.14 to -10.89); employed have lower mean score at all three time points
AgeTimepoint (within subjects)1.25, 22.4123.63120.0622Baseline (mean 84.69 SD 8.62) vs post-treatment (mean 65.47, SD 6.89), P = 0.138Baseline vs follow-up (mean 53.30 SD 7.41), P = 0.011Post treatment vs follow-up, P = 0.013
Living alone (between subjects)1, 188.1670.010Living alone vs with someone mean difference1 34.92 (95%CI: 9.25 to 60.59); living alone have higher score at all three timepoints
Employment (between subjects)1, 1814.5550.001Employed vs unemployed mean difference1 -35.13 (95%CI: -54.47 to -15.78); employed have lower mean score at all three time points
Higher EducationTimepoint (within subjects)1.22, 20.7823.50620.0682Baseline (mean 84.60 SD 8.89) vs post-treatment (mean 65.38, SD 7.64), P = 0.165Baseline vs follow-up (mean 52.48, SD 8.31), P = 0.014Post treatment vs follow-up, P = 0.008
Living alone (between subjects)1, 177.3180.015Living alone vs with someone mean difference1 36.75 (95%CI: 8.09 to 65.41); living alone have higher score at all three timepoints
Employment (between subjects)1, 1710.3700.005Employed vs unemployed mean difference1 -31.02 (95%CI: -51.34 to -10.70); employed have lower mean score at all three time points
CORE totalGenderTimepoint1.47, 32.3020.02820.9382Baseline (mean 73.88, SD 4.56) vs post-treatment (mean 47.42, SD 5.11), P < 0.001Baseline vs follow-up (mean 48.04, SD 5.25), P < 0.001Post treatment vs follow-up, P = 1.0
Age Timepoint1.47, 32.2320.97520.3642Baseline (mean 73.88, SD 4.48) vs post-treatment (mean 47.42, SD 4.95), P < 0.001Baseline vs follow-up (mean 48.04, SD 5.15), P < 0.001Post treatment vs follow-up, P = 1.0
BSI totalAgeTimepoint2, 460.2850.753Baseline (mean 22.64, SD 2.06) vs post-treatment (mean 18.60, SD 2.06), P = 0.041Baseline vs follow-up (mean 16.60, SD 2.09), P = 0.001Post treatment vs follow-up, P = 0.406
GenderTimepoint2, 461.0270.366Baseline (mean 22.64, SD 2.03) vs post-treatment (mean 18.60, SD 2.09), P = 0.026Baseline vs follow-up (mean 16.60, SD 2.07), P = 0.001Post treatment vs follow-up, P = 0.411
Higher educationTimepoint2, 442.8110.071Baseline (mean 22.58, SD 2.19) vs post-treatment (mean 18.21, SD 2.15), P = 0.028Baseline vs follow-up (mean 16.75, SD 2.11), P = 0.003Post treatment vs follow-up, P = 0.661
Marital statusTimepoint2, 463.1460.052Baseline (mean 22.64, SD 2.05) vs post-treatment (mean 18.60, SD 2.08), P = 0.040Baseline vs follow-up (mean 16.60, SD 2.08), P = 0.002Post treatment vs follow-up, P = 0.434