Case Control Study
Copyright ©The Author(s) 2022.
World J Psychiatry. Jul 19, 2022; 12(7): 904-914
Published online Jul 19, 2022. doi: 10.5498/wjp.v12.i7.904
Table 1 Association analysis for four target single-nucleotide polymorphisms and schizophrenia risk, n (%)1
SNP
Genotype/allele
SCZ (n = 443)
HC (n = 511)
P value
OR (95%CI)
HWE test for controls
rs11917047 (PTPRG)AA219 (49.4)259 (50.7)1.00 (ref)0.151
AG183 (41.3)200 (39.1)0.4311.12 (0.85-1.47)
GG41 (9.3)52 (10.2)0.7130.92 (0.58-1.45)
A621 (70.1)718 (70.3)1.00 (ref)
G265 (29.9)304 (29.7)0.8851.02 (0.83-1.24)
rs2239681 (IGF2)AA156 (35.2)177 (34.6)1.00 (ref)0.104
AG211 (47.6)232 (45.4)0.6671.07 (0.80-1.43)
GG76 (17.2)102 (20.0)0.4470.87 (0.59-1.26)
A523 (59.0)586 (57.3)1.00 (ref)
G363 (41.0)436 (42.7)0.5670.95 (0.79-1.14)
rs3842756 (INSIGF)CC405 (91.4)475 (93.0)1.00 (ref)0.409
CT38 (8.6)36 (7.0)0.3191.28 (0.79-2.08)
TT----
C848 (95.7)986 (96.5)1.00 (ref)
T38 (4.3)36 (3.5)0.3291.27 (0.79-2.04)
rs61955196 (ABCB9)CC157 (35.4)202 (39.5)1.00 (ref)0.513
CG213 (48.1)244 (47.7)0.2971.16 (0.88-1.55)
GG73 (16.5)65 (12.7)0.037a1.54 (1.03-2.30)
C527 (59.5)648 (63.4)1.00 (ref)
G359 (40.5)374 (36.6)0.042a1.22 (1.01-1.47)