Magnesium-L-threonate exhibited a neuroprotective effect against oxidative stress damage in HT22 cells and Alzheimer’s disease mouse model

Figure 3 Magnesium-L-threonate administration prevented the apoptosis and regulated the apoptotic-associated proteins expression in the amyloid β_25-35-administrated HT22 cells. A, B: The apoptosis rate of each group; C: Protein band images of B-cell lymphoma 2 (Bcl-2), Bcl-2-associated X (Bax) and glyceraldehyde-3-phosphate dehydrogenase in each group; D: The Bcl-2 protein expression level of each group; E: The Bax protein expression level of each group. n = 3. ^aP < 0.05, ^bP < 0.01, ^cP < 0.001 vs former group. Aβ: Amyloid β; MgT: Magnesium-L-threonate; Bcl-2: B-cell lymphoma 2; Bax: Bcl-2-associated X; GAPDH: glyceraldehyde-3-phosphate dehydrogenase.