Studying the relationship between clinical features and mental health among late-onset myasthenia gravis patients

Table 3 Multivariate logistic model of the clinical determinants of anxiety/depression in myasthenia gravis patients

Variables	Model 1		Model 2
	OR (95%CI)	P value	OR (95%CI)	P value
Anxiety
Gender	0.96 (0.45-2.07)	0.917	0.65 (0.25-1.68)	0.372
Age at onset	1.04 (1.02-1.07)	0.002b	1.02 (0.99-1.05)	0.305
Disease duration	0.93 (0.88-0.98)	0.070	0.97 (0.90-1.04)	0.414
BMI	1.10 (0.99-1.23)	0.075	1.05 (0.92-1.21)	0.485
Anti-AChR Ab	1.02 (1.00-1.05)	0.092	1.02 (0.99-1.05)	0.274
QOL-15	1.10 (1.05-1.16)	< 0.001c	1.10 (1.04-1.15)	< 0.001c
Depression
Gender	0.82 (0.36-1.82)	0.636	0.56 (0.19-1.64)	0.293
Age at onset	1.03 (1.00-1.06)	0.022a	1.03 (0.99-1.06)	0.162
Disease duration	0.98 (0.93-1.03)	0.418	1.06 (0.98-1.15)	0.172
BMI	1.05 (0.93-1.17)	0.440	0.97 (0.83-1.13)	0.678
Anti-AChR Ab	1.10 (0.99-1.04)	0.387	1.01 (0.97-1.05)	0.582
QOL-15	1.19 (1.10-1.28)	< 0.001c	1.20 (1.10-1.30)	< 0.001c

^aP < 0.05.

^bP < 0.01.

^cP < 0.001.

Model 1: Unadjusted; Model 2: Adjusted for possible confounders including gender, age at onset, body mass index, and anti-acetylcholine receptor antibody. BMI: Body mass index; QOL-15: Myasthenia Gravis Quality of Life 15 questionnaire; OR = exp (β).