Retrospective Study
Copyright ©The Author(s) 2021.
World J Psychiatr. Apr 19, 2021; 11(4): 124-132
Published online Apr 19, 2021. doi: 10.5498/wjp.v11.i4.124
Table 2 Epidemiological profiles and clinical features of 14 patients with chronic serotonin syndrome
Parameters
n (%)
Age in yr, mean ± SD44.1 ± 11.6
Sex, M:F9:5 (1.8:1)
Duration of illness in wk13.5 ± 5.8
Clinical characteristics
Tremor14 (100)
Hyperreflexia14 (100)
Clonus13 (93)
Spasticity-rigidity11 (79)
Tachycardia9 (64)
Generalized pain7 (50)
Insomnia7 (50)
Irritability-restlessness7 (50)
Stiffness 6 (43)
Diaphoresis6 (43)
Gait disturbances5 (36)
Bowel disturbances5 (36)
Dizziness 4 (29)
Sexual dysfunctions3 (21)
Nystagmus3 (21)
Hypertension 2 (14)
Incoordination2 (14)
Fatigue2 (14)
Fulfilments of SS criteria
Hunter criteria14 (100)
Sternbach’s criteria 11 (78)
Serotonergic agents implicated in 14 cases
Amitriptyline6 (43)
Tramadol5 (36)
Valproate5 (36)
Paroxetine 2 (14)
Sertraline2 (14)
Citalopram1 (7)
Fluoxetine1 (7)