Systematic Reviews
Copyright ©The Author(s) 2021.
World J Psychiatr. Dec 19, 2021; 11(12): 1407-1424
Published online Dec 19, 2021. doi: 10.5498/wjp.v11.i12.1407
Table 2 Extracted data from studies that evaluated psychoeducation in patients with bipolar disorder
Ref.
BD
Sample size, N (P × C)
Age in years (P × C)
Female frequency (%) (P × C)
Intervention
Applied scales/parameters
Results
Zhang et al[14], 2019I e II35 × 3934.2 × 34.657.1 × 46.2SCITYMRSP = 0.21
HDRSP = 0.11
FASTP < 0.001
TMTAP = 0.77
SDMTP = 0.09
HVLT-RP = 0.09
SCWTP = 0.054
Wiener et al[15], 2017ND32 × 2924 × 23.8183.3 × 76.2PMBDHDRSP = 0.028
YMRSP = 0.879
Cardoso et al[16], 2015ND32 × 2924.09 × 24.0365.6 × 72.4PMBDBRIANP = 0.88
HARSP = 0.175
YMRSP = 0.576
HDRSP = 0.074
Cardodo et al[17], 2014ND32 × 2924.09 × 24.0365.6 × 72.4PMBDHDRSP = 0.001
YMRSP = 0.102
Faria et al[18], 2014II32 × 2924.09 × 24.0372.4 × 65.6PMBDBRIANP = 0.01
Depressive symptomsP = 0.001
Kurdal et al[19], 2014ND40 × 4037.17 × 33.935 × 40PMBDBDFQP > 0.005
Javadpour et al[20], 2013I e II45 × 4124.4/23.223 × 21PMBDWHOQOL-BREFP < 0.001
MARSP = 0.008
HospitalizationsP < 0.001
de Barros Pellegrinelli et al[21], 2013I e II32 × 2343.43 × 43.7423 × 15PMBDHDRSP = 0.820
YMRSP = 0.716
SASP = 0.114
GAFP = 0.586
CGIP = 0.026
Candini et al[22], 2013I e II57 × 4541.5 × 44.852.6 × 48.9PMBDHospitalizationsP = 0.001
Number of days of hospitalizationP = 0.001
Colom et al[11], 2009I e II60 × 6034.03 × 34.2663.3 × 63.3PMBDNew mood episodeP = 0.002
HospitalizationsP = 0.023
Number of days of hospitalizationP = 0.047
Colom et al[23], 2003I25 × 2535.36 × 34.4864 × 60PMBDMood episodes in the treatment phaseP = 0.003
Mood episodes after 2 yrP = 0.008
Depressive episodesP = 0.004
HospitalizationsP = 0.001
Colom et al[24], 2003I e II60 × 6023.25 × 22.2663.3 × 63.3PMBDNew mood episodeP = 0.001
HospitalizationsP = 0.05
Number of days of hospitalizationP = 0.05
Dalum et al[25], 2018ND23 × 2441 × 4546 × 44IMRIMRS-PP = 0.14
IMRS-SP = 0.76
Depp et al[26], 2015I e II51 × 6346.9 × 48.153.7 × 63.4PRISMYMRSP = 0.004
MADRSP = 0.036
IISP = 0.636
Lauder et al[27], 2015I e II71 × 5939.87 × 41.3573 × 76MS–PLUSASRMSP = 0.02
MADRSP = 0.003
MOS-SSSP = 0.003
MARSP = 0.001
GPFP = 0.003
Torrent et al[28], 2013I e II159 × 8040.59 × 40.4757.1 × 57.5FRFASTP = 0.002
HDRSP > 0.05
YMRSP > 0.05
HospitalizationsP > 0.05
Smith et al[29], 2011I e II24 × 2642.7 × 44.754.2 × 69.2BBOFASTP = 0.15
GAFP = 0.21
SAIP = 0.44
WHOQOL-BREFP = 0.25
Sylvia et al[30], 2011I e II4 × 660 × 50.275 × 33NEW TXMADRSP = 0.10
LIFE-RIFTP = 0.014
D'Souza et al[31], 2010I27 × 3140.7 × 39.551.85 × 51.61SIMSEP-BDARSP = 0.001
New mood episodeP = 0.015
Time between mood episodesP = 0.001
Castle et al[32], 2010I e II42 × 4241.6 × 42.679 × 26MAPSMood episodeP = 0.003
Depressive symptomsP = 0.003
Knowledge about illnessP > 0.05
ESM-PAP = 0.024
ESM-NAP = 0.001
So et et al[46], 2021I e II38 × 2635.8 × 43.178.9 × 73.1LGPMedication adherenceP > 0.05
Sajatovic et al[33], 2009I e II80 × 8041.13 × 4073.75 × 87.5LGPDAIP = 0.366
SRTABP = 0.577
GASP = 0.382
Miklowitz et al[34], 2007I e II163 × 13040.1 × 40NDIPIRemission of symptoms 1 yrP = 0.001
Miklowitz et al[35], 2007I e II84 × 68ND59 × 59IPILIFE-RIFTP = 0.006
González Isasi et al[36], 2014I20 × 2043.35 × 39.2545 × 50CBTSTAI-SP = 0.062
YMRSP = 0.009
BDIP = 0.131
ISP = 0.001
Parikh et al[37], 2012I e II109 × 9540.9 × 40.953.2 × 63.2CBTLIFEP > 0.05
CARS-MP = 0.089
HDRSP = 0.089
Zaretsky et al[38], 2008I e II40 × 39NDNDCBTCARS-MP = 0.001
HDRSP = 0.001
Proudfoot et al[39], 2012ND139 × 13435.3 × 40.966.9 × 69.4BEPGADSP > 0.05
WSASP > 0.05
SWLSP > 0.05
BRIEF IPQP = 0.001
Aubry et al[40], 2012I e II50 × 3546 × 5266 × 62.9LGPHospitalizationsP = 0.001
Number of hospitalizationsP = 0.009
Gonzalez et al[41], 2007I e II11 × 1140.5 × 41.045.45 × 45.45IOMGAFP = 0.65
CGI-BDP = 0.06
Depressive symptomsP = 0.005
Miklowitz et al[42], 2003I31 × 7035.6 × 36.658 × 66FFTSADS-CP = 0.001
New mood episodeP = 0.001
MTSP = 0.001
Pakpour et al[43], 2017I e II134 × 13641.8 × 41.255.2 × 50.7GPMARSP = 0.001
YMRSP = 0.001
CGIP = 0.001
QoL.BDP = 0.001
Petzold et al[45], 2019I e II39 × 3444.32 × 42.6943.6 × 47.1GPNew mood episodeP = 0.175
YMRSP = 0.241
HDRSP = 0.58
SF-36P = 0.359
Morriss et al[7], 2016I e II153 × 15144.2 × 46·560 × 56GPTime between mood episodesP = 0.012
SOFASP > 0.05
SASP > 0.05
Kessing et al[44], 2014I72 × 8664.1 × 6361.1 × 48.8GPTime between mood episodesP = 0.014
HospitalizationsP = 0.064
Gumus et al[47], 2015I e II41 × 4138.7 × 40.0540.5 × 56.1GPNumber of mood episodesP = 0.208
Eker et al[48], 2012ND35 × 3634.57 × 36.5454.3 × 52.8GPANTP < 0.005
MARSP < 0.005
Perry et al[49], 1999I34 × 3544.1 × 4568 × 69GPTime between manic episodesP = 0.008
Time between depressive episodesP = 0.19
ANT: Attitudes towards neuroleptic treatment; ASRMS: Altman self-rating mania scale; ARS: Medication adherence scale; B: Baseline; BBO: Beating bipolar online; BD: Bipolar disorder; BDG: Bipolar disorder group; BDI: Beck depression inventory; BDFQ: Bipolar Disorder Functioning Questionnaire; BEP: Bipolar Education Program; BDNF: Brain-Derived Neurotrophic Factor; BRIAN: Biological Rhythm Interview of Assessment in Neuropsychiatry; BRIEF IPQ: The Brief Illness Perception Questionnaire; C: Controls; CARS-M: Clinician-Administered Rating Scale for Mania; CBT: Cognitive-behavioral therapy; CC: Collaborative care; CGI-BD: Clinical Global Impression Scale for Bipolar Disorder; DAI: Drug Attitude Inventory; EDM: Education about Disorders and Medications; ESM-PA: With in person positive affect as measured by using Experience Sampling Method; ESM-NA: Within-person negative affect as measured by using Experience Sampling Method; FAST: Functional Assessment Test; FFT: Family-focused treatment; FR: Functional remediation; GADS: The Goldberg Anxiety and Depression Scale; GAF: Global Assessment of Functioning; GAS: Global Assessment Scale; HVLT-R: Hopkins Verbal Learning Tests-Revised; GDNF: Glial cell line-derived neurotrophic factor; GPF: Global Measure of Psychosocial Functioning; GP: Group Psychoeducation; HARS: Hamilton Anxiety Rating Scale; HDRS: Hamilton Depression Rating Scale; IOM: Integrative Outpatient Model; IMR: Illness Management and Recovery program; IMRS–P: Illness Management and Recovery Scale–participants’ version; IMRS–S: Illness Management and Recovery Scale–staffs; IPI: Intensive Psychosocial Intervention; IS: Maladjustment scale; IRSRT: Interpersonal and social rhythm therapy; LGP: Life Goals Program; LIFE: Longitudinal Interval Follow-up Evaluation; LIFE-RIFT: The Range of Impaired Functioning Tool; MADRS: Montgomery–Asberg Depression Rating Scale; MOSSF-36: Medical Outcomes Survey Short-form General Health Survey; MTS: Maintenance Treatment Scale; MARS: Medication Adherence Rating Scale; MAPS: Monitoring mood and activities (M), assessing prodromes (A), preventing relapse (P) and setting Specific, Measurable, Achievable, Realistic, Time-framed (SMART) goals (S); MARS: Medication adherence rating scale; MS-PLUS: MoodSwings-Plus; MOS-SSS: Medical Outcomes Study Social Support Survey; ND: Not described; NEW TX-Program: Nutrition/weight loss, Exercise, and Wellness Treatment; NGF: Nerve growth factor; P: Patients; PMBD: Psychoeducation Manual For Bipolar Disorder; PRISM: Personalized Real-Time Intervention for Stabilizing Mood , QoL.BD: Quality of Life in Bipolar Disorder scale; SAI: Schedule for Assessment of Insight; SADS-C: Schedule for Affective Disorders and Schizophrenia, Change Version; SAS: Social Adjustment Scale; SCIT: Social cognition and Interaction Training; SCWT: Stroop Color-Word Test; SDMT: Symbol Digit Modalities Test; SIMSEP-BD: Systematic Illness Management Skills Enhancement Program Bipolar Disorder; SF-36: 36-Item Short Form Survey; SOFAS: Social and Occupational Functioning Assessment Scale; SRTAB: Self-reported treatment adherence behaviours; STAI-S: State Trait Anxiety Inventory; SWLS: The Satisfaction with Life Scale; TMTA: Trail Making Test-A; WHOQOL–BREF: World Health Organization Quality of Life, Brief version; WSAS: The Work and Social Adjustment Scale; YMRS: Young Mania Rating Scale.