Differential aberrant connectivity of precuneus and anterior insula may underpin the diagnosis of schizophrenia and mood disorders

doi:10.5498/wjp.v11.i12.1274

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World Journal of Psychiatry

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2220-3206

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Baishideng Publishing Group Inc, 7041 Koll Center Parkway, Suite 160, Pleasanton, CA 94566, USA

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World J Psychiatr. Dec 19, 2021; 11(12): 1274-1287
Published online Dec 19, 2021. doi: 10.5498/wjp.v11.i12.1274

Table 5 Connections significantly different from zero in the schizophrenia group

Connections	Mean	P value
dACC→DLPFC	0.172	0.004^b
Pc→DLPFC	-0.384	0.001^b
dACC⊃	-0.189	0.009^b
aI→dACC	-0.303	0.013^a
Pc→dACC	-0.366	0.001^b
DLPFC→aI	0.110	0.039^a
dACC→aI	0.126	0.026^a

^aP < 0.05.

^bP < 0.01.

^cP < 0.001.

⊃: Self inhibitory connection; DLPFC: Dorsolateral prefrontal cortex; VLPFC: Ventrolateral prefrontal cortex; dACC: Dorsal Anterior cingulate cortex; aI: Anterior insula; Pc: Precuneus.

Citation: Aryutova K, Paunova R, Kandilarova S, Stoyanova K, Maes MH, Stoyanov D. Differential aberrant connectivity of precuneus and anterior insula may underpin the diagnosis of schizophrenia and mood disorders. World J Psychiatr 2021; 11(12): 1274-1287
URL: https://www.wjgnet.com/2220-3206/full/v11/i12/1274.htm
DOI: https://dx.doi.org/10.5498/wjp.v11.i12.1274