Identification of key genes involved in post-traumatic stress disorder: Evidence from bioinformatics analysis

Table 3 The most significantly enriched pathways of differentially expressed genes associated with post-traumatic stress disorder

Term	Pathway	P value	Genes
			Upregulated	Downregulated
mmu04010	MAPK signaling pathway	1.51E–08	Crkl, Fgf12, Mras, Mapt, Ntrk2, Dusp8, Ptpn5, Map3k4, Mapk8ip2, Dusp7	Chuk, Egf, Egfr, Ikbkg, Kras, Nfkb1, Prkca, Pla2g4a, Sos1, Map3k8, Stk3, Tab2, Dusp16, Raf1, Taok1
mmu04014	Ras signaling pathway	1.84E–07	Fgf12, Grin2b, Mras, Pgf, Ptpn11, Gng13	Chuk, Egf, Egfr, Gab1, Ikbkg, Insr, Kras, Nfkb1, Pik3ca, Prkca, Pla2g4a, Sos1, Rassf5, Tbk1, Raf1, Rab5a
mmu04012	ErbB signaling pathway	3.85E–06	Camk2b, Cdkn1b, Crkl	Egf, Egfr, Gab1, Kras, Pik3ca, Prkca, Sos1, Tgfa, Raf1