Statins role in cancer prevention and development-recent meta-analyses

doi:10.5497/wjp.v2.i4.100

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World Journal of Pharmacology

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2220-3192

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Baishideng Publishing Group Inc, 7041 Koll Center Parkway, Suite 160, Pleasanton, CA 94566, USA

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World J Pharmacol. Dec 9, 2013; 2(4): 100-106
Published online Dec 9, 2013. doi: 10.5497/wjp.v2.i4.100

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Figure 1 Mutated p53 and the mevalonate pathway in tumor progression. Mutated p53 actively promotes cancer progression, particularly in breast cancer. Controlled by the sterol regulatory element-binding proteins (SREBP) mutated p53 disrupts the mammary tissue architecture by up-regulation of the mevalonate pathway[28].

Citation: Künzl M, Wasinger C, Hohenegger M. Statins role in cancer prevention and development-recent meta-analyses. World J Pharmacol 2013; 2(4): 100-106
URL: https://www.wjgnet.com/2220-3192/full/v2/i4/100.htm
DOI: https://dx.doi.org/10.5497/wjp.v2.i4.100