Structure-function relationship in viral RNA genomes: The case of hepatitis C virus

Figure 4 Long-range RNA-RNA interactions in the hepatitis C virus genome. Detailed diagram of the interacting network in the genomic hepatitis C virus RNA. The minimum region for internal ribosome entry site (IRES) activity is marked. The 3’ end of the viral genome, containing both the cis-acting replicating element (CRE) and the 3’ untranslatable region (UTR), is included. Functional RNA domains involved in the establishment of long-distant contacts are indicated. Figure adapted from[5].