Regression of cardiovascular remodeling in hypertension: Novel relevant mechanisms

doi:10.5494/wjh.v6.i1.1

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Feb 23, 2016 (publication date) through Dec 24, 2024

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World Journal of Hypertension

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2220-3168

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Baishideng Publishing Group Inc, 7041 Koll Center Parkway, Suite 160, Pleasanton, CA 94566, USA

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World J Hypertens. Feb 23, 2016; 6(1): 1-17
Published online Feb 23, 2016. doi: 10.5494/wjh.v6.i1.1

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Figure 1 Rho kinase activation and downstream effects on cardiovascular remodeling in hypertension (as well as in cardiovascular disease). GEFs: Guanine nucleotide exchange factors; GAPs: GTPase activating proteins; GTP: Guanosine-triphosphate; GDP: Guanosine-diphosphate; MYPT1: Myosin binding subunit of myosin light chain phosphatase 1; MLC2: Myosin light chain 2; ERM: Ezrin/radixin/moesin; SMC: Smooth muscle cell. Adapted from references[2,47,144,145].

Citation: Jalil JE, Ocaranza MP. Regression of cardiovascular remodeling in hypertension: Novel relevant mechanisms. World J Hypertens 2016; 6(1): 1-17
URL: https://www.wjgnet.com/2220-3168/full/v6/i1/1.htm
DOI: https://dx.doi.org/10.5494/wjh.v6.i1.1