Noncanonical intercellular communication in immune response

Figure 2 Trogocytosis/ membrane exchange/stripping. A: During trogocytosis the recipient cell acquires membrane bound molecules from donor cell. The process of internalization of donor cell membrane is similar to phagocytosis and depends on actin ring contraction and small GTPases; B: During APC/T cell interaction the T cell may acquire MHC/peptide complexes and co-stimulatory molecules. Subsequently, such T cells can prime/activate naïve T cells in the absence of APCs, and/or by interacting with activated T cells lead to propagation of immune response[16,20]. APC: Antigen presenting cell; MHC: Major histocompatibility complex.