Pharmacology of cancer chemotherapy drugs for hyperthermic intraperitoneal peroperative chemotherapy in epithelial ovarian cancer

Figure 2 Pharmacokinetic study of concentration versus time for intraperitoneal paclitaxel. The chemotherapy agent at 30 mg/m² was instilled directly into the peritoneal cavity as rapidly as possible in a 1.5% dextrose peritoneal dialysis solution. The concentration of paclitaxel was determined in peritoneal fluid and in plasma for 24 h[51].