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©The Author(s) 2015.
Figure 14 Genotype of individual BFU-E in polycythemia vera and essential thrombocythemia with granulocytes heterozygous for the JAK2V617F mutation (less than 50% JAK2V617F mutation load) show that polycythemia vera patients are heterozygous/homozygous and essential thrombocythemia patients heterozygous for the JAK2V617F somatic mutation.
ET: Essential thrombocythemia; PV: Polycythemia vera; WT: Wild type; BFU-e: Burst forming units erythropoiesis.
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Citation: Michiels JJ, Valster F, Wielenga J, Schelfout K, Raeve HD. European
vs 2015-World Health Organization clinical molecular and pathological classification of myeloproliferative neoplasms. World J Hematol 2015; 4(3): 16-53 - URL: https://www.wjgnet.com/2218-6204/full/v4/i3/16.htm
- DOI: https://dx.doi.org/10.5315/wjh.v4.i3.16