Granulysin and its clinical significance as a biomarker of immune response and NK cell related neoplasms

Figure 5 Trend of serum granulysin. A: In patients with allo-hematopoietic stem cell transplantation (HSCT) (n = 21) and auto-HSCT (n = 5). Serum granulysin is elevated 2 wk after allogeneic hematopoietic stem cell transplantation, but not autologous hematopoietic stem cell transplantation; B: With the grade of graft-versus-host disease (GVHD). Serum granulysin and the grade of GVHD were plotted and their correlation coefficient was calculated (r = 0.59). The serum granulysin level of patients with grade 2 or more is significantly higher than that of patients with grade 1 or no GVHD.