Current approach to relapsed acute lymphoblastic leukemia in children

doi:10.5315/wjh.v3.i3.49

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Aug 6, 2014 (publication date) through Nov 15, 2024

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World Journal of Hematology

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2218-6204

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Baishideng Publishing Group Inc, 7041 Koll Center Parkway, Suite 160, Pleasanton, CA 94566, USA

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World J Hematol. Aug 6, 2014; 3(3): 49-70
Published online Aug 6, 2014. doi: 10.5315/wjh.v3.i3.49

Table 6 Children oncology group approach to relapsed acute lymphoblastic leukaemia[29]

Relapse	Site	Time		MRD
B-lineage	Marrow	Early	Chemotherapy vs chemotherapy plus novel agents	Negative	SCT
				Positive	Bridging study before HSCT
		Late	Chemotherapy vs chemotherapy plus novel agents	Negative	Continuation therapy
				Positive	SCT
	IEM	Early	Chemotherapy vs chemotherapy plus novel agents	Any	SCT
				Any	SCT
		Late	Chemotherapy vs chemotherapy plus novel agents	Negative	Continuation therapy
				Positive	SCT
T-lineage	Marrow	Early	Chemotherapy vs chemotherapy plus novel agents	Negative	SCT
		Late		Positive	Bridging study before HSCT
	IEM	Early	Chemotherapy vs chemotherapy plus novel agents
		Late		Any	SCT

IEM: Isolated extramedullary; SCT: Hematopoietic stem cell transplantation.

Citation: Fuster JL. Current approach to relapsed acute lymphoblastic leukemia in children. World J Hematol 2014; 3(3): 49-70
URL: https://www.wjgnet.com/2218-6204/full/v3/i3/49.htm
DOI: https://dx.doi.org/10.5315/wjh.v3.i3.49