Gemcitabine cures metastatic hepatic carcinoma and bone metastasis

Figure 2 Liver aspiration. A: Liver tissue with tumor arranged in solid sheet on the left side of the picture (HE stain, x 200); B: High power view shows tumor cells with hyperchromatic nuclei and high nucleus-to-cytoplasm (N/C) ratio (HE stain, x 400). Two patches of necrosis are found in the lower and right upper part; C: Tumor cells in solid nest with hyperchromatic nuclei and high N/C ratio. The right side is normal liver tissue (HE stain, x 400); D: AE1/AE3 (IHC stain, x 400). Focal cytoplasmic positive reaction (white arrow).