Management of adult Langerhans cell histiocytosis based on the characteristic clinical features

doi:10.5315/wjh.v2.i3.89

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World Journal of Hematology

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2218-6204

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Baishideng Publishing Group Inc, 7041 Koll Center Parkway, Suite 160, Pleasanton, CA 94566, USA

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World J Hematol. Aug 6, 2013; 2(3): 89-98
Published online Aug 6, 2013. doi: 10.5315/wjh.v2.i3.89

Table 2 Therapeutic options in the treatment of adult langerhans cell histiocytosis

Protocol	Drugs	Ref.
A1 protocol	VBL/PSL	[6]
JLSG-96	VCR/AraC/MTX/6MP/PSL	[13]
Cladribine-based	2CDA/PSL, 2CDA/AraC	[37-41]
Clofarabine-based	Clofarabine	[43,44]
JLSG-special C	VBL/MTX/6MP/PSL	[11]
Others	AraC alone	[45]
Molecular targetting	Vemurafenib	[46]
Bone therapy	Zoledronic acid	[47]

VBL: Vinblastine; PSL: Prednisolone; MTX: Methotrexate; 6MP: 6-mercatopurine hydrate; 2CDA: 2-deoxychloroadenosine.

Citation: Imashuku S, Shimazaki C, Tojo A, Imamura T, Morimoto A. Management of adult Langerhans cell histiocytosis based on the characteristic clinical features. World J Hematol 2013; 2(3): 89-98
URL: https://www.wjgnet.com/2218-6204/full/v2/i3/89.htm
DOI: https://dx.doi.org/10.5315/wjh.v2.i3.89