Aspirin responsive platelet thrombophilia in essential thrombocythemia and polycythemia vera

Table 3 Incidence of thrombotic and bleeding complications in the prospective 1975-1996 Rotterdam study of 68 essential thrombocythemia patients during a median follow-up of 6.7 years according to treatment strategy n (events/100 persons per year)

Treatment strategy	Duration of follow-up (person/yr)	Thrombotic complication	Bleeding complications
Asymptomatic (14 patients)
Watchful waiting	127	27 (33.3)	2 (1.6)
Symptomatic (54 patients)
Low dose aspirin	139	5 (3.6)	10 (7.2)
Platelet reduction	113	10 (8.9)	2 (1.8)
Low dose aspirin + platelet reduction	40	0 (0)	4 (10)
Total	419	42 (100)	18 (100)

Originated from[61,71].