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©The Author(s) 2024.
World J Hematol. May 1, 2024; 11(1): 89084
Published online May 1, 2024. doi: 10.5315/wjh.v11.i1.89084
Published online May 1, 2024. doi: 10.5315/wjh.v11.i1.89084
Table 1 Demographic and clinical characteristics of Crohn disease patients coronavirus disease 2019 + underwent autologous hematopoietic stem cell transplantation (2013-2021; 19/50 pts)
Age (yr) | Sex | HSCT date | Elapsed months | Vaccina | Label vaccine (n) | CD status | COVID-19 | Months HSCT to COVID | Vaccination at infection time | Symptoms COVID-19 + | Treatment COVID-19+ | CD Status before COVID-19 pts + | CD Status after COVID-19 pts + | Delayed symptoms after COVID-19 | |
5 | 41-45 | F | 2015 | 84 | No | 0 | Remission | Yes | 76 | No | Fever, flu-like symptoms, cough, body aches | 0 | Remission | Remission | 0 |
7 | 56-60 | M | 2015 | 78 | Yes | (2) Az | Remission | Yes | 77 | Yes | Fever, body aches, fatigue | 0 | Remission | Remission | 0 |
8 | 51-55 | M | 2015 | 77 | No | 0 | Remission | Yes | 76 | No | Severe body aches, severe headache, physical and mental fatigue and diarrhea | 0 | Remission | Remission | Fatigue, muscle weakness, shortness of breath |
12 | 31-35 | M | 2016 | 71 | No | 0 | Relapsed | Yes | 59 | No | Flu symptoms | 0 | Relapsed | Relapsed | 0 |
14 | 41-45 | M | 2016 | 69 | Yes | Relapsed | Yes | 68 | Yes | Coryza and sore throat | 0 | Relapsed | Relapsed | 0 | |
15 | 51-55 | F | 2016 | 69 | Yes | 0 | Remission | Yes | 68 | No | Headache, diarrhea, hospital stay 5 days | Iver, Cort e Azitro | Remission | Remission | Sleep disorders, headache |
20 | 31-35 | F | 2017 | 57 | Yes | (2) Az (1) Pf | Remission | Yes | 56 | Yes | Headache, rashes, fever, cough and sore throat | Azitro, Cort | Remission | Remission | Loss of taste, nausea and alopecia |
22a | 26-30 | F | 2017 | 55 | No | 0 | Remission | Yes | 41 | No | Flu-like symptoms, nausea, fatigue | 0 | Remission | Remission | 0 |
22b | 26-30 | F | 2017 | 55 | Yes | (2) Az | Remission | Yes | 54 | Yes | Cough | 0 | Remission | Remission | Diarrhea |
24 | 41-45 | F | 2017 | 50 | Yes | (2) Az (1) Pf | Relapsed | Yes | 49 | Yes | Fever, sore throat, body aches, vomiting, headache, cough and worsening diarrhea | 0 | Relapsed | Relapsed | Cough, headache and dizziness, burning in the throat |
27 | 41-45 | F | 2018 | 45 | Yes | (1) Az | Remission | Yes | 32 | No | Body ache and sore throat | Azitro, Iver | Remission | Remission | 0 |
29 | 36-40 | F | 2018 | 42 | Yes | (2) Az (1) Pf | Relapsed | Yes | 41 | Yes | Sore throat, cough, runny nose, body ache, fever, indisposition | 0 | Relapsed | Relapsed | 0 |
31 | 36-40 | M | 2019 | 33 | Yes | 0 | Relapsed | Yes | 24 | Yes | Shortness of breath, cough and asthma | Azitro, Cort | Relapsed | Relapsed | Coagnitive disorders |
33 | 16-20 | F | 2019 | 32 | No | 0 | Relapsed | Yes | 12 | No | Headache, sneezing, body ache, runny nose | 0 | Relapsed | Relapsed | 0 |
34 | 31-35 | F | 2019 | 30 | Yes | (3) Pf | Relapsed | Yes | 29 | Yes | 0 | Relapsed | Relapsed | 0 | |
40a | 31-35 | F | 2020 | 24 | No | 0 | Relapsed | Yes | 6 | No | Loss of taste and smell, fever, tiredness, diarrhea, sore throat, headache and body pain. Loss of taste and smell, fever, tiredness, diarrhea, sore throat, headache and body pain | 0 | Remission | Relapsed | Muscle weakness, sleep and cognitive disturbances with CD symptoms |
40b | 31-35 | F | 2020 | 24 | Yes | (2) Az (1) Pf | Relapsed | Yes | 23 | Yes | Sore throat, cough, runny nose, fever, headache and body ache | 0 | Relapsed | Relapsed | Muscle weakness, sleep and cognitive disturbances with CD symptoms |
41 | 51-55 | F | 2020 | 24 | Yes | (2) Pf | Relapsed | Yes | 23 | Yes | Fever, body aches, sore throat and weakness | 0 | Relapsed | Relapsed | Diarrhoea, severe abdominal pain |
43 | 46-50 | M | 2020 | 16 | Yes | 0 | Relapsed | Yes | 6 | No | Fever, stuffy nose, loss of smell and taste, and muscle aches | 0 | Remission | Relapsed | 0 |
44 | 36-40 | M | 2020 | 14 | Yes | 0 | Relapsed | Yes | 4 | No | Fever, headache, lack of appetite, tiredness, cough, weakness | 0 | Remission | Relapsed | 0 |
50 | 31-35 | F | 2021 | 5 | Yes | (2) Az (1) Pf | Remission | Yes | 3 | Yes | Fever, headache, body ache, sore throat, cough, tiredness, chest pain, vomiting, diarrhea | 0 | Remission | Remission | 0 |
- Citation: Ruiz MA, Kaiser Junior RL, Piron-Ruiz L, Pinho TS, Castiglioni L, de Quadros LG. COVID-19 impact in Crohn’s disease patients submitted to autologous hematopoietic stem cell transplantation. World J Hematol 2024; 11(1): 89084
- URL: https://www.wjgnet.com/2218-6204/full/v11/i1/89084.htm
- DOI: https://dx.doi.org/10.5315/wjh.v11.i1.89084