Updates on management of gliomas in the molecular age

Figure 4 Pilocytic astrocytoma. A: Axial T2-weighted scan through the cerebellum demonstrating a well-defined solid-cystic mass in the left cerebellar hemisphere that is heterogeneous onT2-weighted sequence and causes mass effect to the 4^th ventricle. The solid component is minimally hyperintense compared to the gray matter; B: An axial T2 FLAIR image through the same level better demonstrates the area of T2 hyperintensity beyond the tumor margin, suggestive of edema; C: An axial post-contrast T1-weighted sequence through the same level demonstrates intense enhancement of the solid component of the tumor; D and E: The axial diffusion image and ADC map (E) through the same level show no diffusion restriction; F: The mean transit time map demonstrates increased transit time within the solid component of the tumor; G: The cerebral blood volume map shows that the tumor has very low cerebral blood volume. Citation: Bag AK, Chiang J, Patay Z. Radiohistogenomics of pediatric low-grade neuroepithelial tumors. Neuroradiology 2021; 63: 1185-1213. Copyright ©2021 The Authors. Published by Springer Nature[58] (Supplementary material).