Selective granulocyte and monocyte apheresis in inflammatory bowel disease: Its past, present and future

Figure 1 Photograph of Adacolumn and scanning electron photomicrograph of the acetate beads after treatment. Adacolumn is filled with cellulose acetate beads of 2 mm in diameter (adsorptive carriers) bathed in sterile saline. The blood from the antecubital vein of one arm flows into the column and returns to the antecubital vein in the contralateral arm. A: A low power view (400 ×) of the acetate beads in a column after treatment with cells covering the surface of the carrier; B: Viewed at 10000 ×. Neutrophils were adsorbed onto the beads; C: Viewed at 12000 ×. Activated monocyte/macrophages are seen (taken by Dr. A. Saniabadi of Japan Immunoresearch Laboratories). Modified from reference[31].