Perfusion computed tomography in renal cell carcinoma

Figure 5 Perfusion parameters showing partial response with anti-angiogenic therapy. Comparison of perfusion parameters in right side chromophobe renal cell carcinoma (same patient as shown in Figure 2) after start of anti-angiogenic therapy shows partial response as permeability (PMB) in follow-up scan (B) at 6 mo interval decreased compared to baseline scan (A). The PMB measured 18.72 mL/100 mL per minute at baseline (A) while in follow-up scan (B), PMB was 13.2 mL/100 mL per minute. There was no interval change in lesion size and would have been labeled as stable disease in absence of perfusion parameters. MIP: Maximum peak intensity; TTP: Time to peak; BF: Blood flow; BV: Blood volume; MTT: Mean transit time; CT: Computed tomography.