Progress in atherosclerotic plaque imaging

Figure 3 Example of plaque characterization trough integrated backscatter ultrasonography. A: Large plaque (arrow); A1: An integrated backscatter (IB) image at autopsy; A2: A color-coded map constructed from A1, based on the five IB categories and conventional 2D echo findings; A3: van Gieson staining of the same segment as the IB measurement (bar = 1 mm); B: Intimal fibrosis (arrow); B1: An IB image during life; B2: A color-coded map constructed from B1; B3: Masson’s trichrome staining of the same segment; C: Intimal hyperplasia consisting of smooth muscle cells (arrow); C1: An integrated backscatter image during life; C2: A color-coded map constructed from C1; C3: Masson’s trichrome staining of the same segment (reprint with permission)[32].