Non-invasive MRI assessment of the articular cartilage in clinical studies and experimental settings

Figure 5 High resolution MRI demonstrates cartilage erosion and proliferation in rat knee joint. A: Sagittal view MRI of a rat knee with a medial meniscal tear. White arrow shows neo-cartilage proliferation and black arrow shows articular cartilage loss; B: Histology section of the medial tibial condyle stained with Toluidine blue (× 100), 28 d after meniscal tear. Cartilage erosion (black arrow) and neo-cartilage proliferation (white arrow) are seen in the tibia cartilage. MTC: Medial tibia condyle; MFC: Media femur condyle. This animal model has been described in reference 22 (Wang et al[22] 2006).