Early repolarization syndrome: A cause of sudden cardiac death

Figure 2 Schematic representation of the possible mechanisms underlying J-wave occurrence. Action potentials from epicardium and endocardium from normal individuals (left) and early repolarization (ER) patients (right) as well as the respective electrocardiograms are shown. A prominent phase I-notch and the loss of epicardial dome in phase - 2 (thick arrow) results in transmural dispersion of repolarization (dashed arrows) and appearance of the J-wave and ST-segment elevation on the surface ECG. AP: Action potential; ECG: Electrocardiogram; ER: Early repolarization; RP: Resting potention. Reproduced with permission, from ref.[67].