Mechanisms underlying the impaired contractility of diabetic cardiomyopathy

Figure 1 Average intracellular Ca²⁺ transients and isometric stress. Data were recorded from left ventricular trabeculae of diabetic (red lines) and control (black lines) hearts at 5 Hz, 37 °C, and 1.5 mmol [Ca²⁺]o, 7 trabeculae per group. A: Ca²⁺ transient (340/380 fluorescence ratio); B: Stress; C: Phase plots of the relationship between fluorescence and stress. The arrows indicate the direction of time, and the dashed grey lines accentuate the slope of the relaxation component. (Modified from Zhang et al[23]).