High-density lipoprotein and atherosclerosis: Roles of lipid transporters

Figure 5 Fukuoka University apoA-I mimetic peptide effects on cellular cholesterol effluxes in cells that express ATP-binding A1 and ATP-binding G1. COS-7 cells were transiently transfected with an empty vector (mock) or with human ATP-binding cassette transporter A1 (ABCA1) and ATP-binding cassette transporter G1 (ABCG1) cDNAs. Cholesterol efflux was determined after incubation with apoA-I or FAMP. Results are expressed as mean ± SD. ^aP < 0.05 vs FAMP in mock; ^bP < 0.01 vs BSA; ^dP < 0.01 vs FAMP in mock; ^fP < 0.01 vs apoA-I in mock. Graph modified from the paper by Uehara et al[82]. FAMP: Fukuoka University ApoA-I mimetic peptide; BSA: bovine serum albumin; apoA-I: apolipoprotein A-I; FAMP: Fukuoka University ApoA-I Mimetic Peptide..