Arrhythmic risk stratification in ischemic, non-ischemic and hypertrophic cardiomyopathy: A two-step multifactorial, electrophysiology study inclusive approach

Figure 1 The PRESERVE EF[24] study’s two-step arrhythmic risk stratification algorithm. In the total sample of patients the estimated prevalence of major arrhythmic events (MAE) during the 32-mo follow-up was 1.5%. Implementation of the algorithm with the detection of the NIRFs in the first step determines the intermediate-risk subpopulation, with the MAE prevalence accounting for 4.4%. In the second step, the Programmed Ventricular Stimulation determines the actual high-risk subpopulation, with a prevalence reaching 22%. Of the 37 patients with implantable cardioverter defibrillator, there were 9 true activations during the 32-mo follow-up. Neither sudden cardiac death(SCD) nor inappropriate ICD activations were observed during follow-up. (Modified with permission from EHJ[24]).