Undiscovered pathology of transient scaffolding t1remains a driver of failures in clinical trials

Figure 4 The artery remodeling in ABSORB cohort B1 trial. A, B: The plaque burden (%) in 44 patients of cohort B1 trial (panel A with the changes at panel B); C, D: The proportion between the lesion components, which was computed by virtual histology-intravascular ultrasound imposed for each patient, but the percentage of each plaque component did not differ significantly between baseline and 24 mo. The depicted results mounted as the mean of the estimated proportions. The figure was adapted from ref. [34]. n: Number of patients; MPA: Mean plaque area; abs: Absolute; rel: Relative; VH-TCFA: Virtual histology-thin-cap fibroatheroma; PB: plaque burden; VH-IVUS: virtual histology-intravascular ultrasound.