Glucagon receptor gene mutations with hyperglucagonemia but without the glucagonoma syndrome

Figure 2 Genetic findings. A: Sequencing results showing a heterozygous 33 nucleotide deletion and 5 point mutations in exon 11 of the GCGR; B: Amino acid sequence showing K349_G359del, E362K, V368L, K381E, S389N in the GCGR. Alignments done using Clustal W multiple sequence alignments software[25]. Numbers indicate the position of the last residue shown along the GCGR cDNA/protein.