Retrospective Study
Copyright ©The Author(s) 2024. Published by Baishideng Publishing Group Inc. All rights reserved.
World J Gastrointest Surg. Apr 27, 2024; 16(4): 1087-1096
Published online Apr 27, 2024. doi: 10.4240/wjgs.v16.i4.1087
Construction of a predictive model for acute liver failure after hepatectomy based on neutrophil-to-lymphocyte ratio and albumin-bilirubin score
Xiao-Pei Li, Zeng-Tao Bao, Li Wang, Chun-Yan Zhang, Wen Yang
Xiao-Pei Li, Li Wang, Department of Family Planning and Assisted Reproductive Technology, The First People’s Hospital of Lianyungang, Lianyungang 222000, Jiangsu Province, China
Zeng-Tao Bao, Department of Gastrointestinal Surgery, The First People’s Hospital of Lianyungang, Lianyungang 222000, Jiangsu Province, China
Chun-Yan Zhang, Department of Laboratory Medicine, The First People’s Hospital of Lianyungang, Lianyungang 222000, Jiangsu Province, China
Wen Yang, Department of Gynecology, The First People’s Hospital of Lianyungang, Lianyungang 222000, Jiangsu Province, China
Author contributions: Li XP designed the study and wrote the manuscript; Bao ZT designed the study and provided clinical data; Wang L and Zhang CY contributed to the data analysis; Yang W and Bao ZT reviewed the research. All authors approved this research.
Institutional review board statement: The study was reviewed and approved by the Ethics Committee of the First People’s Hospital of Lianyungang, No. LW-20231120001-01.
Informed consent statement: As this was a retrospective study, the Ethics Committee of The First People’s Hospital of Lianyungang approved the exemption for informed consent.
Conflict-of-interest statement: The authors declare no conflicts of interest.
Data sharing statement: The data used in this study can be obtained from the corresponding author upon request.
Open-Access: This article is an open-access article that was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution NonCommercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: https://creativecommons.org/Licenses/by-nc/4.0/
Corresponding author: Wen Yang, MBBS, Chief Physician, Department of Gynecology, The First People’s Hospital of Lianyungang, No. 192 Tongguanbei Road, Haizhou District, Lianyungang 222000, Jiangsu Province, China. wen_yang0@163.com
Received: January 19, 2024
Peer-review started: January 19, 2024
First decision: February 5, 2024
Revised: February 18, 2024
Accepted: March 21, 2024
Article in press: March 21, 2024
Published online: April 27, 2024
Core Tip

Core Tip: This study aimed to identify independent risk factors associated with acute liver failure (ALF) after complete tumor resection (R0) for hepatocellular carcinoma (HCC) and to investigate their efficacy in predicting the occurrence of ALF after R0 for HCC. The results showed that the prediction model of ALF after R0 surgery for HCC, constructed based on the neutrophil-to-lymphocyte ratio and albumin-bilirubin score, had a good predictive efficacy and is expected to be a promising predictive tool in future clinical work.