Tyrosine isomers and hormonal signaling: A possible role for the hydroxyl free radical in insulin resistance

Figure 7 Relative meta- and ortho-tyrosine content (i. e., ratios of meta- and ortho-tyrosine/total tyrosine) of the cellular proteins of TF-1 cells (A and B, respectively). ^bP < 0.001 vs p- and m-Tyr cultured cells; ^dP < 0.001 vs o-Tyr cultured control cells; ^fP < 0.001 vs p- and o-Tyr cultured erythroblasts; n = 10. Comparisons were performed using ANOVA and Bonferroni’s post-hoc test. Republished with permission of S Karger AG, basel from Mikolás et al[21]. p-Tyr: Para-tyrosine; o-Tyr: Ortho-tyrosine; m-Tyr: Meta-tyrosine.