Tyrosine isomers and hormonal signaling: A possible role for the hydroxyl free radical in insulin resistance

Figure 4 Effects of treatment with r-mo-erythropoietin on the rate of [3H]-deoxy-D-glucose uptake in 3T3-L1 adipocytes cultured in either normal (5 mmol/L) or high (25 mmol/L) glucose medium (insulin: n = 8 and n = 6; r-mo-erythropoietin: n = 6 and n = 5, respectively). ^aP < 0.05 vs control in the same medium; ^cP < 0.05 between the two media; Comparisons with control were performed using a one-sample t-test; pairwise comparisons between 5 and 25 mmol/L glucose-cultured cells were performed using a paired samples t-test. Republished with permission of Georg Thieme Verlag KG Stuttgart, New York from Mikolás et al[37]. EPO: Erythropoietin.