Tyrosine isomers and hormonal signaling: A possible role for the hydroxyl free radical in insulin resistance

Figure 3 Decrease in homeostasis model of assessment for insulin resistance upon resveratrol treatment. For each participant, the value measured at baseline was subtracted from that measured at week 4 (i.e., Δ HOMA-IR), and then the resulting values were averaged within the respective groups. Values are the means with the standard deviations represented by vertical bars. ^aMean values were significantly different for the resveratrol group vs the placebo group (P = 0.044), comparisons were performed using ANOVA and Bonferroni post hoc tests; P < 0.05 was regarded as statistically significant. Republished with permission of Cambridge University Press from Brasnyó et al[18]. HOMA-IR: Homeostasis model of assessment for insulin resistance.