Research progress on the effect of pyroptosis on the occurrence, development, invasion and metastasis of colorectal cancer

Figure 6 Pyroptosis and the colorectal cancer tumor microenvironment. A: Granzyme-mediated pathway; B: Non-canonical pathway; C: Canonical pathway. NLRP: Nucleotide-binding oligomerization domain (NOD)-like receptor family, pyrin domain-containing protein; DAMP: Damage-associated molecular pattern; TNF: Tumor necrosis factor; TRADD: Tumor necrosis factor receptor type 1-associated death domain protein; ASC: Apoptosis-associated speck-like protein containing a CARD; PAMP: Pathogen-associated molecular pattern; IL: Interleukin. Citation: The authors have obtained the permission for figure using from the BioRender.com (Supplementary material)[203].