Retrospective Study
Copyright ©The Author(s) 2024. Published by Baishideng Publishing Group Inc. All rights reserved.
World J Gastrointest Oncol. Jan 15, 2024; 16(1): 110-117
Published online Jan 15, 2024. doi: 10.4251/wjgo.v16.i1.110
Clinical value of oral contrast-enhanced ultrasonography in diagnosis of gastric tumors
Chuan-Yu Wang, Xiao-Jing Fan, Fei-Liang Wang, Yue-Yue Ge, Zhao Cai, Wei Wang, Xin-Ping Zhou, Jun Du, De-Wei Dai
Chuan-Yu Wang, Xiao-Jing Fan, Fei-Liang Wang, Yue-Yue Ge, Zhao Cai, De-Wei Dai, Department of Ultrasound Medicine, Beijing Hospital, Beijing 100005, China
Wei Wang, Department of Gastroscopy, Beijing Hospital, Beijing 100005, China
Xin-Ping Zhou, Department of General Surgery, Beijing Hospital, Beijing 100005, China
Jun Du, Department of Pathology, Beijing Hospital, Beijing 100005, China
Author contributions: Wang CY and Dai DW designed the research study; Wang CY, Fan XJ, and Wang FL performed the research; Wang CY, Fan XJ, Wang FL, Ge YY, Cai Z, Wang W, Zhou XP, Du J, and Dai DW analyzed the data and wrote the manuscript; all authors have read and approved the final manuscript.
Institutional review board statement: The study was reviewed and approved by the Beijing Hospital Institutional Review Board.
Informed consent statement: All study participants, or their legal guardian, provided informed written consent prior to study enrollment.
Conflict-of-interest statement: There is no conflict of interest to disclose.
Data sharing statement: No additional data are available.
Open-Access: This article is an open-access article that was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution NonCommercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: https://creativecommons.org/Licenses/by-nc/4.0/
Corresponding author: De-Wei Dai, MD, Chief Physician, Department of Ultrasound Medicine, Beijing Hospital, No. 1 Dahua Road, Dongdan, Dongcheng District, Beijing 100005, China. dai.weide@126.com
Received: September 14, 2023
Peer-review started: September 14, 2023
First decision: October 8, 2023
Revised: November 10, 2023
Accepted: November 15, 2023
Article in press: November 15, 2023
Published online: January 15, 2024
ARTICLE HIGHLIGHTS
Research background

The incidence of gastric cancer remains high, and it is the sixth most common cancer and the fourth leading cause of cancer deaths worldwide. Oral contrast-enhanced ultrasonography is a simple, non-invasive, and painless method for the diagnosis of gastric tumors.

Research motivation

The authors found that oral contrast-enhanced ultrasonography can avoid unnecessary exploratory surgical laparotomy, and provide reliable evidence for diagnosis and treatment of gastric tumors in clinical practice.

Research objectives

This study aimed to explore the diagnostic value of oral contrast-enhanced ultrasonography for the detection of gastric tumors.

Research methods

In this study, a total of 42 gastric tumor patients underwent both oral contrast-enhanced ultrasonography and gastroscopy. The screening results based on oral contrast-enhanced ultrasonography and electronic gastroscopy were compared with those of the postoperative pathological examination.

Research results

Among 42 patients with gastric tumors enrolled in the study, the diagnostic accordance rate was 95.2% for oral contrast-enhanced ultrasonography, and 90.5% for electronic gastroscopy compared with postoperative pathological examination. The Kappa value of consistency test with pathological findings was 0.812 for oral contrast-enhanced ultrasonography and 0.718 for electronic gastroscopy, and there was no significant difference between them.

Research conclusions

In summary, oral contrast-enhanced ultrasonography has several advantages compared to gastroscopy. It is simple, safe, and minimally invasive for detecting gastric tumors, and is suitable for feeble and sick patients who cannot tolerate gastroscopy. The accordance rate of qualitative diagnosis by oral contrast-enhanced ultrasonography was comparable to that of gastroscopy, and it could be used as the preferred method for the early screening of gastric tumors.

Research perspectives

The combined application of oral contrast-enhanced ultrasonography and electronic gastroscopy could improve the accuracy rate of the diagnosis of gastric tumors, provide more reliable evidence for the diagnosis, treatment, and outcome prediction of gastric tumors, and has guiding significance in clinical practice.